Biology Education

Department of Biology | Lund University

Developing Diagnostic Tools for Complement-Mediated Diseases

Are you passionate about immunology and biomedical research? This master’s project offers a hands-on opportunity to contribute to cutting-edge diagnostics for complement-mediated diseases.

The complement system (CS) is a key part of our innate immune defense, responsible for identifying and eliminating harmful pathogens and defective cells. However, the dysregulation of the CS and excessive inflammatory reaction have been linked to several diseases, such as IgA nephropathy, metabolic diseases and congenital disorders. Thus, there is a burgeoning need to develop new diagnostic tools. 

In this project, you will:

🔬 Develop and characterize monoclonal antibodies against complement factors.

🧪 Design and optimize immunoassays for detecting complement components as disease biomarkers.

🧬 Gain experience with techniques in molecular and cellular biology, such as cell culture, recombinant protein and antibody production, purification techniques, ELISA, and western immunoblotting, among others.

Your research will contribute to the development of novel diagnostic and therapeutic approaches, with the potential for publication in high-impact journals. This is an excellent opportunity to expand your scientific expertise, work in a collaborative research environment, and make a real impact in biomedical science.

If you are eager to develop innovative diagnostic tools and gain valuable lab experience, we will be very happy to hear from you! 

Who are we?

We are a research group of around 15 people led by Professor Peter Garred and part of the Department of Clinical Immunology at Rigshospitalet and University of Copenhagen. Our focus is innate immunity, with a particular interest in the complement system’s role in health and disease. The group atmosphere is international, informal and friendly, and we are prepared to give you substantial supervision and support regarding your project.

Contact:

Group leader Professor Peter Garred

peter.garred@regionh.dk.

Please include your CV and transcripts in the email

February 7, 2025

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Molecular Biology