We are currently seeking highly motivated and dedicated Master’s student to contribute to research in our well-established group of Clinical Microbiology situated on the Malmö hospital campus. Our group is interested in the research of clinically relevant bacterial species that mainly cause upper and lower airway infections and their interactions with the host. We offer you to join our dynamic team and contribute to the research of pathogenic bacteria.
Our project offers a unique opportunity for Master’s student to gain hands-on experience focused on transcriptional regulators with importance in expression of genes of outer membrane proteins that are essential in host-pathogen interaction. In our proposed project, you would investigate expression regulation in clinically significant bacterium non-typeable Haemophilus influenzae (NTHi). There will be involved gene engineering and molecular biology methods such as PCR, SDS-PAGE, qPCR, western blot, DNA-protein interaction assays, flow cytometry etc. You will also employ functional assays investigating host-pathogen interactions in vitro, such as serum bactericidal assay or adherence to eukaryotic cells. You will get the opportunity to work alongside our experienced lab members, who will train you and guide you while solving the project.
So, if you are a Master’s student looking for a challenging but also rewarding research project, who is interested in bacterial genetics, we encourage you to apply to our project.
Start date: Autumn 2023
References:
Janoušková M. et al. (2022) Gene Expression Regulation in Airway Pathogens: Importance for Otitis Media. Frontiers in Cellular and Infection Microbiology, 12. 10.3389/fcimb.2022.826018
Jalalvand F et al. (2022) Protein domain-dependent vesiculation of Lipoprotein A, a protein that is important in cell wall synthesis and fitness of the human respiratory pathogen Haemophilus influenzae. Frontiers in Cellular and Infection Microbiology, 12. 10.3389/fcimb.2022.984955
More information about our lab you can find at a link: http://research.med.lu.se/kristian-riesbeck
E-Mail: kristian.riesbeck@med.lu.se